Monensin, a small molecule ionophore, can be used to increase high mannose levels on monoclonal antibodies generated by Chinese hamster ovary production cell-lines
Author:
Affiliation:
1. Cell Sciences and Technology, Amgen; 1201 Amgen Court W; Seattle Washington 98119
2. Analytical Sciences, Amgen; 1201 Amgen Court W; Seattle Washington 98119
Funder
Amgen
Publisher
Wiley
Subject
Applied Microbiology and Biotechnology,Bioengineering,Biotechnology
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3. Effect of monensin on Mason-Pfizer monkey virus glycoprotein synthesis;Chatterjee;J Virol,1982
4. Use of ionophores in lactating dairy cattle: A review;Duffield;Can Vet J,2000
5. Inhibition of N-linked oligosaccharide processing does not prevent the secretion of thyroglobulin. A study with swainsonine and deoxynojirimycin;Franc;Eur J Biochem,1986
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