Lymphangioleiomyomatosis in lymph node cytology: Another “Floating Island” to visit

Author:

Jawaid Tabinda1ORCID,Swanson Amy A.2,Bois Melanie C.2,Folpe Andrew L.2,Rivera Michael2,Hartley Christopher P.2,Sturgis Charles D.2ORCID

Affiliation:

1. Genetics Laboratory Mayo Clinic Rochester Minnesota USA

2. Anatomic Pathology Mayo Clinic Rochester Minnesota USA

Abstract

AbstractLymphangioleiomyomatosis (LAM) is a rare disease with variable presentations. The neoplastic cells in LAM demonstrate a unique and diagnostically important “myomelanocytic” phenotype. Cytologic reports of LAM are infrequent and have not in the past emphasized the floating island pattern in which circumscribed aggregates of lesional cells are rimmed by appliques of flattened endothelium. This case illustrates the cytology of LAM and emphasizes that the floating island cytoarchitectural pattern more classically associated with entities such as hepatocellular carcinomas may be seen in cytological preparations of LAM at unanticipated body sites.

Publisher

Wiley

Subject

General Medicine,Histology,Pathology and Forensic Medicine

Cited by 1 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Pathomorphological Characteristic of Pulmonary Lymphangioleiomyomatosis;Journal of Anatomy and Histopathology;2024-01-19

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