Genome‐Wide Polygenic Score Predicts Large Number of High Risk Individuals in Monogenic Undiagnosed Young Onset Parkinson's Disease Patients from India-Reference-Cited by-同舟云学术

Genome‐Wide Polygenic Score Predicts Large Number of High Risk Individuals in Monogenic Undiagnosed Young Onset Parkinson's Disease Patients from India

Published:2022-07-10 Issue:11 Volume:6 Page:2101326
ISSN:2701-0198
Container-title:Advanced Biology
language:en
Short-container-title:Advanced Biology

Author:

Kukkle Prashanth Lingappa¹²³,Geetha Thenral S.⁴,Chaudhary Ruchi⁵,Sathirapongsasuti Jarupon F.⁵,Goyal Vinay⁶⁷⁸^ORCID,Kandadai Rukmini Mridula⁹^ORCID,Kumar Hrishikesh¹⁰,Borgohain Rupam⁹,Mukherjee Adreesh¹¹,Oliver Merina⁴^ORCID,Sunil Meeta⁴^ORCID,Mootor Mohammed Faizal Eeman⁴^ORCID,Kapil Shruti⁴^ORCID,Mandloi Nitin⁴,Wadia Pettarusp M.¹²,Yadav Ravi¹³^ORCID,Desai Soaham¹⁴^ORCID,Kumar Niraj³^ORCID,Biswas Atanu¹¹^ORCID,Pal Pramod Kumar¹³^ORCID,Muthane Uday B.¹⁵,Das Shymal Kumar¹¹,Sakthivel Murugan Sakthivel M.⁴,Peterson Andrew S.⁵,Stawiski Eric W.⁵,Seshagiri Somasekar¹⁶^ORCID,Gupta Ravi⁴^ORCID,Ramprasad Vedam L.⁴,(PRAI) Parkinson Research Alliance of India¹⁷

Affiliation:

1. Department of Neurology Manipal Hospital Miller Road Bangalore 560052 India

2. Department of Neurology Parkinson's Disease and Movement Disorders Clinic Bangalore 560010 India

3. Department of Neurology All India Institute of Medical Sciences Rishikesh 249201 India

4. Research and Diagnostics Department MedGenome Labs Pvt Ltd Bangalore 560099 India

5. Research Department MedGenome Inc. 348 Hatch Drive Foster City CA 94404 USA

6. Department of Neurology All India Institute of Medical Sciences (AIIMS) New Delhi 110608 India

7. Department of Neurology Medanta Hospital New Delhi 110047 India

8. Department of Neurology Medanta The Medicity Gurgaon 122006 India

9. Department of Neurology Nizams Institute of Medical Sciences (NIMS) Hyderabad 500082 India

10. Department of Neurology Institute of Neurosciences Kolkata Kolkata 700007 India

11. Department of Neurology Bangur Institute of Neurosciences and Institute of Post Graduate Medical Education and Research (IPGME&R) Kolkata 700020 India

12. Department of Neurology Jaslok Hospital and Research Centre Mumbai 400026 India

13. Department of Neurology National Institute of Mental Health and Neurosciences (NIMHANS) Bangalore 560029 India

14. Department of Neurology Shree Krishna Hospital and Pramukhswami Medical College Bhaikaka University Karamsad 388325 India

15. Department of Neurology Parkinson and Ageing Research Foundation Bangalore 560095 India

16. GenomeAsia 100K Foundation Foster City USA

17. Hyderabad 500084 India

Publisher

Wiley

Subject

General Biochemistry, Genetics and Molecular Biology,Biomedical Engineering,Biomaterials

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/adbi.202101326

Reference75 articles.

1. The genetic architecture of Parkinson's disease

2. Parkinson's disease: Evidence for environmental risk factors

3. Meta‐analysis of early nonmotor features and risk factors for Parkinson disease

4. Clinical use of current polygenic risk scores may exacerbate health disparities

5. Clinical Study of 668 Indian Subjects with Juvenile, Young, and Early Onset Parkinson’s Disease

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