Obsessive Compulsive Neurosis in Identical Twins

Author:

Marks I. M.,Crowe M.,Drewe E.,Young J.,Dewhurst W. G.

Abstract

This paper reports a case which is noteworthy for two unrelated reasons, one genetic and the other therapeutic. The genetic interest lies in the rare instance of an identical twin with obsessive compulsive neurosis whose twin brother had a similar illness. The therapeutic interest focuses on clinical changes which occurred during unsuccessful treatment by desensitization and by aversion relief. These changes aid our understanding of compulsive behaviour and the difficulties in its treatment. At one stage in treatment independence was noted between anxiety and compulsions which suggested that compulsive behaviour need not always be maintained by its anxiety-reducing properties. The case history will first be described and discussed from the genetic point of view. The second part of this paper will focus on the unrelated aspect of treatment.

Publisher

Royal College of Psychiatrists

Subject

Psychiatry and Mental health

Cited by 67 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Fear conditioning and extinction in obsessive-compulsive disorder: A systematic review;Neuroscience & Biobehavioral Reviews;2021-10

2. Anxiety and affective disorder comorbidity related to serotonin and other neurotransmitter systems: obsessive–compulsive disorder as an example of overlapping clinical and genetic heterogeneity;Philosophical Transactions of the Royal Society B: Biological Sciences;2013-04-05

3. Genetics of Obsessive-Compulsive Disorder;Psychiatric Clinics of North America;2010-03

4. The genetics of obsessive compulsive disorder: A review of the evidence;American Journal of Medical Genetics Part C: Seminars in Medical Genetics;2008

5. Evidence for a heritable unidimensional symptom factor underlying obsessionality;American Journal of Medical Genetics Part B: Neuropsychiatric Genetics;2007-12-28

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