Anatomical Correlates of Improvement After Leucotomy

Author:

McLardy T.,Meyer A.

Abstract

Out of 95 leucotomy cases of which the brains and clinical records have been collected at this laboratory, 45 were cases with post-operative survival of over 5 months, and more than 20 of these showed some degree of clinical improvement. Such numbers now make worth while an attempt to ascertain whether or not any attribute common to the lesions is a prerequisite to clinical improvement; whether or not the degree of improvement tends to vary with any qualitative or quantitative feature of the lesions; and whether or not any such relationship between lesions and improvement which is revealed holds good in equal degree for each of the main types of functional-psychosis. Over 20 of the same 45 cases had a recorded post-operative change of personality, so that relationship of post-operative personality change to the leucotomy lesions can conveniently be investigated in the same group of cases. Only some general findings concerning the personality change will, however, be touched on in the present paper.

Publisher

Royal College of Psychiatrists

Subject

General Medicine

Reference16 articles.

1. It should be borne in mind that by the method of selection practically all cases with bilateral involvement of premotor or posterior orbital cortex or the basal ganglia have been excluded from this study.

2. Except in enumerating the total number of segments involved, no account of unilateral damage of segments is taken in this paper because of the generally accepted principle that prefrontal lesions must be bilateral to produce physiological or psychological effects.

3. THE CINGULAR GYRUS: AREA 24

4. Posterior Cuts in Prefrontal Leucotomy: A Clinico-Pathological Study

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