Author:
Waldron John,Bates T. J. N.
Abstract
Desipramine (Pertofran) is a metabolite of imipramine (Tofranil) originally isolated by Herrmann, Schindler and Pulver (1959) and found to be identical with the synthetic compound G.35025. Animal experiments (Gillette et al., 1961) suggest a more rapid action for desipramine, and the majority of clinical trials to date confirm this impression for humans (e.g. Kline et al., 1962; Krakowski, 1963). Some controlled trials, however, (Azima et al., 1962; Hollister et al., 1963) fail to establish that desipramine is either faster acting or more effective than imipramine.
Publisher
Royal College of Psychiatrists
Subject
Psychiatry and Mental health
Reference18 articles.
1. “Clinical trial with desmethylimipramine (G-35025), a new anti-depressive compound.”;Ban;Ibid.,1962
2. Clinical Features of Depression and the Response to Imipramine (“Tofranil”)
3. Amitriptyline in Depressive States
4. “Papierchromatographischer Nachweis von Stoff-wechselprodukten des Tofranil.”;Herrmann;Med. exp.,1959
5. A RATING SCALE FOR DEPRESSION
Cited by
23 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献