The Wassermann and Meinicke Klärungs Reactions (Original M.K.R. Ii and Ford Robertson-Colquhoun Modification) in the Diagnosis of Syphilis

Author:

Thomas John C.,Robertson W. M. Ford

Abstract

Nicole and Fitzgerald's assumption in 1932 that the Wassermann test had at last passed to rest in the limbo of historically interesting experiments can hardly be said to be correct, and the test still remains to-day as the standard method for the sero-diagnosis of syphilis. At the same time the steadily increasing specificity of flocculation tests and their value as ancillary procedures cannot be denied, and the accepted diagnostic ideal is a parallel examination by one of these and by the Wassermann test.

Publisher

Royal College of Psychiatrists

Subject

General Medicine

Reference11 articles.

1. “Wassermann-fast “sera are known. In our experience they are not so common as “Meinicke-fast “sera.

2. It is not really practicable to determine the sensitivity of either of these tests, as opposed to their specificity, in a mental hospital. This is properly done on new, untreated infections in a V.D. clinic. An old case which has been adequately treated will in all probability have a negative W.R., although the serum may, in some cases, become “Meinicke-fast “. A case in which the mental symptoms are directly referable to a luetic infection will show a positive W.R. in the spinal fluid irrespective of the M.K.R. Menninger and Bromberg (1935) found a positive W.R. in 100% of neurosyphilitics (500 cases of asymptomatic neuro-syphilis, tabes, general paralysis, tabo-paresis and meningo-vascular syphilis). It is with this aspect that one is properly concerned in a mental hospital.

3. The commonly recommended acid-bichromate mixture for cleaning Meinicke tubes is not the best. Immediately after use they should be washed out with cold tap-water and immersed in 10% hydrogen peroxide overnight. They are then washed with hot water and soap, rinsed clean with cold tap-water, run through distilled water and dried. If they are dried in a hot-air oven the temperature should not be above 110° C.

Cited by 2 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Klassische Serologie der Syphilis;Syphilis und Ulcus Molle;1962

2. SPOT TEST FOR SYPHILIS;Archives of Dermatology and Syphilology;1948-05-01

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