Insulin Shock Therapy

Author:

Thomas John C.,Gilsenan Bernard,Hewitt E. J. C.

Abstract

Insulin shock treatment of schizophrenia is to-day a recognized part of our therapeutic armamentarium in mental disease, and with selected cases is yielding results which are more encouraging than those given by other methods. At the same time the method is largely empirical, and the theories of its mode of action are only equalled in number by the hypothetical causes of the disease itself.

Publisher

Royal College of Psychiatrists

Subject

General Medicine

Reference4 articles.

1. The remaining patient—a male in catatonic stupor—will be discussed elsewhere.

2. We have used the Hagedorn-Jensen blood-sugar apparatus designed by Dr. H. J. Fuchs, and sold by Messrs. Baird & Tatlock, Ltd. The use of the special automatic 0.1 ml. pipette is a great asset when a number of estimations have to be made (our preliminary work has already entailedmore than a thousand blood-sugar analyses),as are the funnel-topped filtration-boiling tubes. The lipped precipitation tubes are designed to hold the 6 ml. of ZnSO4-NaOH mixture together with the blood sample, but do not allow for the extra 1 ml. odd of distilled water which is blown in from the automatic pipette. We have had to discard these tubes therefore, and have substitutedordinary Pyrex test-tubes.

3. It is interesting to note that one ætiological theory of the disease postulates a disturbance of the vegetative nervous system, with a parallel adrenaline imbalance.

4. It is important to stress the necessity for using chemicals of the utmost purity for this technique. With these, the automatic pipette and the needle-dropper, one can obtain exact duplicate results on any given sample of blood.

Cited by 9 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Disorders of Glucose Metabolism in Brain Dysfunction;Biology of Brain Dysfunction;1973

2. The Positive Correlation between Insulin Resistance and Duration of Hospitalization in Untreated Schizophrenia;British Journal of Psychiatry;1971-04

3. A re-evaluation of glucose tolerance in schizophrenia;Journal of Psychiatric Research;1969-05

4. Literaturverzeichnis;Experimentelle Grundlagen der Multifaktoriellen Genese der Schizophrenie;1963

5. Plasma free fatty acid concentrations (FFA) in chronic schizophrenia before and after insulin stimulation;Journal of Psychiatric Research;1962-09

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