Sub-Acute Sclerosing Leuco-Encephalitis: A Clinical and Pathological Report of Two Cases

Abstract

The first object of this paper is to describe the clinical and pathological features of two cases of sub-acute sclerosing leuco-encephalitis (first distinguished by van Bogaert in 1945). A second object is to compare these features with those of the Dawson inclusion type of sub-acute encephalitis (Dawson, 1933, 1934; Brain, Greenfield and Russell, 1943, 1948; Greenfield, 1950; Malamud, Haymaker and Pinkerton, 1950), and the final object is to emphasize the importance of mental change, when associated with motor symptoms, in the diagnosis of both these forms of encephalitis.