Abstract
A retrospective study of 92 patients admitted with mania, aged over 65 years of age, found that 26% had no prior history of affective illness; 30% had previously only experienced depression, and half of these had at least three episodes of depression before the first manic illness. Patients with a family history of affective disorders had a significantly earlier age of onset of illness. There was evidence of cerebral organic impairment in 24% of the patients, and this group had a significantly later age of onset of illness. Prognosis was good, with only 8% still in hospital at six months. Half of the patients were started on lithium prophylaxis, but this did not significantly alter the number of readmissions. A quarter of those started on lithium developed evidence of lithium toxicity.
Publisher
Royal College of Psychiatrists
Subject
Psychiatry and Mental health
Reference35 articles.
1. Lithium prophylaxis in recurrent affective disorders;Angst;Acta Psychiatrica Scandinavica,1970
2. A study of bipolar (manic depressive) and unipolar recurrent depressive psychosis;Perris;Acta Psychiatrica Scandinavica,1966
3. The natural history of mental disorder in old age;Roth;Journal of Mental Science,1955
4. Familial Transmission of Major Affective Disorders
5. Changing Patterns in Mental Illness in the Elderly
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