Perivascular Cavitation of the Basal Ganglia in Gargoylism

Abstract

Perivascular cysts visible to the naked eye have been described in the brain of several cases of gargoylism (Lindsayet al., 1948; Hendersonet al., 1952; Naidoo, 1953). In most instances they were small, not exceeding 1 mm. in diameter and confined to the white matter of the cerebral hemispheres. The present case is remarkable for the exceptional size of the perivascular cysts which had led to gross bilateral cavitation of the thalamus and putamen.