Author:
Alexopoulos George S.,Kiosses Dimitris N.,Sirey Jo Anne,Kanellopoulos Dora,Novitch Richard S.,Ghosh Samiran,Seirup Joanna K.,Raue Patrick J.
Abstract
SummaryChronic obstructive pulmonary disease (COPD) is often complicated by depression and exemplifies the challenge in managing chronic illnesses that require active patient participation in care. In a clinical trial (NCT00151372), we compared a novel personalised intervention for depression and COPD (PID-C) targeting treatment adherence with treatment as usual (TAU). In 138 patients with major depression and severe COPD, PID-C led to a higher remission rate and a greater reduction in depressive symptoms and in dyspnoea-related disability than TAU over 28 weeks and 6 months after the last session. If replicated, PID-C may serve as a care model for patients with both depression and medical illnesses with a deteriorating course.
Publisher
Royal College of Psychiatrists
Subject
Psychiatry and Mental health
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