Author:
Cuijpers Pim,Smit Filip,Bohlmeijer Ernst,Hollon Steven D.,Andersson Gerhard
Abstract
BackgroundIt is not clear whether the effects of cognitive–behavioural therapy and
other psychotherapies have been overestimated because of publication
bias.AimsTo examine indicators of publication bias in randomised controlled trials
of psychotherapy for adult depression.MethodWe examined effect sizes of 117 trials with 175 comparisons between
psychotherapy and control conditions. As indicators of publication bias
we examined funnel plots, calculated adjusted effect sizes after
publication had been taken into account using Duval & Tweedie's
procedure, and tested the symmetry of the funnel plots using the Begg
& Mazumdar rank correlation test and Egger's test.ResultsThe mean effect size was 0.67, which was reduced after adjustment for
publication bias to 0.42 (51 imputed studies). Both Begg & Mazumbar's
test and Egger's test were highly significant
(P<0.001).ConclusionsThe effects of psychotherapy for adult depression seem to be
overestimated considerably because of publication bias.
Publisher
Royal College of Psychiatrists
Subject
Psychiatry and Mental health
Cited by
316 articles.
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