An Unusual Response to Chlorpromazine Therapy

Abstract

The production of a catatonic-like state in animals by phenothiazines and related compounds (‘experimental catatonia’) is an important laboratory test in the assessment of neuroleptics (Joyce, 1968). This response is, however, uncommon in humans who are receiving therapeutic doses of this type of drug. Such a case is described, and some of the literature concerning this subject is reviewed.