Author:
Turek Ibrahim,Kurland Albert A.,Hanlon Thomas E.,Bohm Mark
Abstract
Although accounts of neurological complications resulting from the use of neuroleptic drugs have consistently appeared in the psychiatric literature since the introduction of reserpine in the 1930's, serious concern about the permanence of these effects has been a rather recent development. As early as 1956, reports by Ey, Faure, and Rappard (10) and by Hall, Jackson, and Swain (13) called attention to the persistence of extrapyramidal symptoms several months after the cessation of extended chlorpromazine treatment. Emphasis on the persistence of dyskinetic symptoms after extended treatment subsequently appeared in reports by Broussolle and Rosier (2), Sigwald, Bouttier, and Courvoisier (20), and Ayd (1). In a survey of reversible and irreversible dyskinesia after treatment with reserpine, chlorpromazine, perphenazine and electroconvulsive therapy, Uhrbrand and Faurbye (22) noted the late appearance of the complication and termed it ‘tardive dyskinesia’.
Publisher
Royal College of Psychiatrists
Subject
Psychiatry and Mental health
Reference27 articles.
1. ‘Prominent or complex dyskinesias in the aged.’;Paulson;Geriatrics,1968
2. Only three patients had been previously hospitalized at Spring Grove. The neuroleptic drug intake figures that follow were obtained by converting all drug dosages to equivalent chiorpromazine dosage.
3. Throughout the text and tables, treatment phases are coded as follows: o = no drug; N = neuroleptic drug; A = antiparkinson drug; and 2 = double the original dosage.
4. ‘Syndromes extra-pyramidaux permanents consécutifs a l'administration prolongée de neuroleptiques.’;Wertheimer;Schweizersche Archiv für Neurologie, Neurochiurigie und Psychiatrie,1965
5. The bucco-linguo-masticatory syndrome as a side-effect of neuroleptics therapy
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