On the Slowness of Action of Tricyclic Antidepressant Drugs

Author:

Oswald Ian,Brezinova Vlasta,Dunleavy D. L. F.

Abstract

It is widely believed that tricyclic antidepressants such as imipramine bring little benefit for ten days, that three or four weeks are needed to be sure, and that five or six weeks are needed to get the patient really back to health. Why should it take so long? Is it even true? If true it seems remarkable that such a challenge should have been largely ignored by theorists content to rest their arguments upon acute experiments with animals.

Publisher

Royal College of Psychiatrists

Subject

Psychiatry and Mental health

Reference16 articles.

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