A Genetic Model of Narcolepsy

Author:

Leckman James F.,Gershon Elliot S.

Abstract

SummaryAn analysis of recently published family history data on rapid eye movement (REM) narcolepsy was undertaken to determine the goodness-of-fit of a multifactorial (MF) model of inheritance. The analysis revealed that a two-threshold MF model can successfully account for the prevalence of REM narcolepsy and other disorders of excessive sleep (DES) observed in the first-degree relatives of the REM narcoleptic probands studied.

Publisher

Royal College of Psychiatrists

Subject

Psychiatry and Mental health

Cited by 12 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. HLA in Narcolepsy in Japan;HLA in Narcolepsy;1988

2. Sleep Disorders: Sleep Apnea and Narcolepsy;Annals of Internal Medicine;1987-03-01

3. The Neurobiology of the Narcoleptic Syndrome;International Journal of Neuroscience;1984-01

4. Insomnia and Other Sleep Disorders;Medical Clinics of North America;1982-09

5. Canine model of narcolepsy: Genetic and developmental determinants;Experimental Neurology;1982-03

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