Author:
Lynch D. M.,Eliatamby C. L. S.,Anderson A. A.
Abstract
SummaryThe efficacy of intramuscular pipothiazine palmitate (PP) in the management of aggressive mentally handicapped patients was examined in a double-blind, placebo-controlled, cross-over study, in which 30 patients received each treatment for 13 weeks. A target symptom scale of aggressiveness (TSA) and a clinical global impression scale of efficacy were rated at monthly intervals, and an extra-pyramidal side-effects scale weekly. The patients showed marked improvement during treatment with PP, which was assessed as superior to placebo. Individual and total TSA scores were also reduced compared to placebo.
Publisher
Royal College of Psychiatrists
Subject
Psychiatry and Mental health
Reference20 articles.
1. Efficacy of SCH-12679 in the management of aggressive mental retardates;Albert;Current Therapeutic Research,1977
2. Depot pipotiazine: thirteen years later;Ayd;International Drug Therapy Newsletter,1983
3. Psychiatric Disturbance in Mentally Handicapped Patients
4. TREATMENT OF HUMAN AGGRESSION WITH MAJOR TRANQUILIZERS, ANTIDEPRESSANTS, AND NEWER PSYCHOTROPIC DRUGS
5. Depot tranquillisers for disturbed behaviour.
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