Author:
Byrne Majella,Browne Roy,Mulryan Niamh,Scully Ann,Morris Mary,Kinsella Anthony,Takei Noriyoshi,McNeil Tom,Walsh Dermot,O'Callaghan Eadbhard
Abstract
BackgroundControversy continues regarding an association between obstetric complications and risk of schizophrenia in early adult life.AimsTo compare the rate of labour and delivery complications among persons who developed schizophrenia with controls; to establish whether any complication is associated with later schizophrenia.MethodWe located the labour ward records of 431 individuals with schizophrenia and of same-gender controls from the same hospital birth series. Mothers were matched by age, socio-economic group and parity. Individual complications were evaluated blindly using two obstetric complication scales.ResultsOverall, the rate of labour and delivery complications for those who developed schizophrenia did not differ from that of controls. Males who had presented to psychiatric services before the age of 30 had a greater frequency of and more severe labour/delivery complications than their matched controls.ConclusionsOther than among young-onset males we found no increase in labour and delivery complications among cases.
Publisher
Royal College of Psychiatrists
Subject
Psychiatry and Mental health
Cited by
44 articles.
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