Author:
Haug Tone Tangen,Blomhoff Svein,Hellstrøm Kerstin,Holme Ingar,Humble Mats,Madsbu Hans Petter,Wold Jan Egil
Abstract
BackgroundMaintenance of treatment effect is important for the choice of treatment for social phobia.AimsTo examine the effect of exposure therapy and sertraline 28 weeks after cessation of medical treatment.MethodIn this study 375 patients with social phobia were randomised to treatment with sertraline or placebo for 24 weeks, with or without the addition of exposure therapy Fifty-two weeks after inclusion, 328 patients were evaluated by the same psychometric tests as at baseline and the end of treatment (24 weeks).ResultsThe exposure therapy group and the placebo group had a further improvement in scores on social phobia during follow-up: mean change in the Clinical Global Impression – Social Phobia overall severity score was 0.45 (95% CI 016–0.65, P < 0.01) for the exposure group, and 0.25 (95% CI 0.00–0.48, P < 0.05) for the placebo group. At week 52 the sertraline plus exposure group and the sertraline-alone group had a significant deterioration on the 36-item Short Form Health Survey compared with exposure alone.ConclusionsExposure therapy alone yielded a further improvement during follow-up, whereas exposure therapy combined with sertraline and sertraline alone showed a tendency towards deterioration after the completion of treatment.
Publisher
Royal College of Psychiatrists
Subject
Psychiatry and Mental health
Cited by
122 articles.
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