Pick's disease in old age

Abstract

Pick's disease most commonly begins in the midlife period. Sjogren, Sjogren and Lindgren (1952) in their series of 18 anatomically verified cases of Pick's disease found that the average age of onset was 54·5±2·7 years. Escourolle (1956) segregated from the literature 184 cases in which he considered the diagnosis of Pick's disease to be “indisputable” and demonstrated therefrom that the sixth decade is the period of highest incidence. Pick's disease, however, has frequently been reported to erupt in the seventh decade and occasionally in the eighth, ninth and tenth decades. (Bonfiglio, 1926; von Braunmühl, 1928; Moyano, 1932; Sjogren, Sjogren and Lindgren, 1952.)