Report on Short-Action Muscle Relaxant Ro/3/0386 in E.C.T.

Abstract

The use of muscle relaxants as a help in minimizing the hazards of E.C.T. has been reported by a number of workers (Hobson and Prescott, 1947; Davies and Lewis, 1949; Shepherd and Watts, 1949; Smith and Thomas, 1951; and Thompson and Norton, 1951). From these observations the value of such substances in reducing the muscular force of electrically-induced convulsions is clear. Nevertheless the trial of a new substance was embarked upon in order to establish whether it approaches more closely the ideal drug for the purpose.