Histocompatability Antigens and Schizophrenia

Author:

McGuffin Peter,Farmer Anne E.,Rajah S. M.

Abstract

The HLA (Human Leucocyte Antigen) types A and B were studied in 80 patients diagnosed as schizophrenic. There was an increased incidence of HLA-BW5 and a decrease in HLA-AW29 and HLA-BW17 as compared with healthy controls. In the sub-group of patients exhibiting Schneider's first-rank symptoms there was an increased incidence of HLA-A1 with a decrease in HLA-A2 and HLA-BW17.

Publisher

Royal College of Psychiatrists

Subject

Psychiatry and Mental health

Reference9 articles.

1. Schizophrenia as an Immunologic Disorder

2. Schneiderian First-Rank Symptoms and Clinical Prognostic Features in Schizophrenia

3. Schizophrenia; some new aetiological considerations;Burch;British Journal of Psychiatry,1964

4. First-rank symptoms of schizophrenia;Mellor;British Journal of Psychiatry,1970

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