Mianserin Hydrochloride: A Novel Antidepressant

Author:

Coppen Alec,Gupta Ramesh,Montgomery Stuart,Ghose Karabi,Bailey John,Burns Bruce,de Ridder J. J.

Abstract

SummaryThe antidepressant activities of mianserin hydrochloride were investigated and compared with those of amitriptyline. The therapeutic efficacy of the two drugs appeared similar, but the incidence of side-effects was significantly higher with amitriptyline. Plasma levels of mianserin were determined during the trial and were not related to the therapeutic activity of the drug.

Publisher

Royal College of Psychiatrists

Subject

Psychiatry and Mental health

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