Abstract
AIMS AND METHODSTo describe and attempt to quantify the incidence of disinhibitory
reactions to benzodiazepines and to identify those at risk. Medline
search, 1966–January 2002.ResultsThe overall incidence of disinhibitory reactions is small, but those with
impulse control problems, neurological disorders, learning disabilities,
the under 18s and the over 65s are at significant risk.Clinical ImplicationsIt is important to be aware of the ability of benzodiazepines to cause
behavioural disinhibition and to maintain a high degree of vigilance when
these drugs are administered to patients known to be at risk. In patients
who have experienced behavioural disinhibition with benzodiazepines,
antipsychotic drugs should be used to modify behaviour in any future
emergencies.
Publisher
Royal College of Psychiatrists
Subject
Psychiatry and Mental health
Cited by
85 articles.
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