Author:
Isohanni Matti,Lauronen Erika,Moilanen Kristiina,Isohanni Irene,Kemppainen Liisa,Koponen Hannu,Miettunen Jouko,Mäki Pirjo,Räsänen Sami,Veijola Juha,Tienari Pekka,Wahlberg Karl-Erik,Murray Graham K.
Abstract
BackgroundSubtle motor, emotional, cognitive and behavioural abnormalities are often present in apparently healthy individuals who later develop schizophrenia, suggesting that some aspects of causation are established before overt psychosis.AimsTo outline the development of schizophrenia.MethodWe drew on evidence from The Northern Finland 1966 Birth Cohort supplemented by selected findings from other relevant literature.ResultsThe main known risk factors in development of schizophrenia are genetic causes, pregnancy and delivery complications, slow neuromotor development, and deviant cognitive and academic performance. However, their effect size and predictive power are small.ConclusionsNo powerful risk factor, premorbid sign or risk indicator has been identified that is useful for the prediction of schizophrenia in the general population.
Publisher
Royal College of Psychiatrists
Subject
Psychiatry and Mental health
Cited by
32 articles.
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