Author:
Boston Paul F.,Dursun Serdar M.,Reveley Michael A.
Abstract
BackgroundCholesterol plays an important part in cellular structure and function and changes in serum levels may affect neurotransmission in the central nervous system.MethodA medline literature search was made covering the period 1990–95 with systematic searching of citations from the articles identified. Representative articles were selected, focusing on those aspects which had not been thoroughly reviewed elsewhere, namely suicidal ideation, depression, personality and schizophrenia.ResultsLowering cholesterol levels have been associated with an increase in violent deaths in cardiovascular primary prevention studies. However, altered cholesterol levels have also been reported in relation to other psychiatric disorders.ConclusionThere is substantial evidence that serum cholesterol levels may be associated with variations in mental state or personality. Further work is needed to clarify this and to elucidate the mechanisms involved.
Publisher
Royal College of Psychiatrists
Subject
Psychiatry and Mental health
Reference31 articles.
1. Low Serum Cholesterol and Suicide
2. Serum cholesterol and suicidal tendencies in psychiatric inpatients;Modai;Journal of Clinical Psychiatry,1994
3. Lower degree of esterification of serum cholesterol in depression: relevance for depression and suicide research
4. Low serum cholesterol and attempted suicide;Golier;American Journal of Psychiatry,1995
5. Longevity syndromes: familial hypobeta and familial hyperalpha lipoproteinaemia;Glueck;Journal of Laboratory and Clinical Medicine,1976
Cited by
110 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献