Author:
Pourcher Emmanuelle,Baruch Philippe,Bouchard Roch Hugo,Filteau Marie-Josée,Bergeron Danielle
Abstract
BackgroundApart from ageing, the factors associated with vulnerability to the emergence of tardive dyskinesia are poorly defined.MethodRisk factors associated with the presence of a chronic choreic or dystonic disorder were assessed in a cross-sectional comparison of anamnestic and clinical data in a homogeneous group of 64 young psychotic patients (under 40 years of age) on chronic low to moderate doses of neuroleptics.ResultsDyskinetic subjects presented more indirect indicators of occult brain damage, such as a perinatal event or traumatic brain injuries in infancy and early childhood; neurological examination showed more anomalies in dyskinetic patients than in non-dyskinetics, with a higher prevalence of facial release reflexes.ConclusionThese data may support the hypothesis that occult acquired brain damage is important in the genesis of this ‘drug-induced’ disorder.
Publisher
Royal College of Psychiatrists
Subject
Psychiatry and Mental health
Cited by
21 articles.
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