Abstract
In this paper we present a fractional order mathematical model to explain the spread of Hepatitis B Virus (HBV) in a non-constant population. The model we propose includes both vertical and horizontal transmission of the infection and also vaccination at birth and vaccination of the susceptible class. We also use a frequency dependent transmission rate in the model. We give results on existence of equilibrium points of the model and analyze the stability of the disease-free equilibrium. Finally, numerical simulations of the model are presented.
Publisher
Communications Faculty of Sciences University of Ankara Series A1 Mathematics and Statistics
Reference36 articles.
1. Anderson, R. M., May, R. M., Vaccination and herd immunity, Nature, 318 (1985), 323-329.
2. Diekmann, O., Heesterbeek, J. A. P., Metz, J. A. J., On the definition and computation of the basic reproduction ratio $R_{0}$ in models for infectious diseases in heterogeneous populations, J. Math. Biol., 28 (1990), 365-382.
3. Ding, Y., Ye, H., A fractional-order differential equation model of HIV infection of $CD4^{+}T-$Cells, Mathematical and Computer Modeling, 50 (2009), 386-392.
4. El-Saka, H. A. A., The fractional-order SIS epidemic model with variable population size, Journal of Egyptian Mathematical Society, 22(1) (2014), 50-54.
5. European Center for Disease Prevention and Control, Hepatitis B - Annual Epidemiological Report (2016). https://www.ecdc.europa.eu/en/publications-data/hepatitis-b-annual epidemiological-report-2016-2014-data / Accessed 21.09.2020.
Cited by
1 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献