Berberine ameliorates hyperglycemia in alloxan-induced diabetic C57BL/6 mice through activation of Akt signaling pathway
Author:
Affiliation:
1. Laboratory of Pharmacology & Toxicology, School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, China
2. Chengdu Military General Hospital, Chengdu 610083, China
Publisher
Japan Endocrine Society
Subject
Endocrinology,Endocrinology, Diabetes and Metabolism
Link
http://www.jstage.jst.go.jp/article/endocrj/58/9/58_K11E-024/_pdf
Reference35 articles.
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3. 3. R. V. Dimlich, S. F. Townsend and F. D. Reilly (1982) Mast cell degranulation, hepatic glycogen depletion, and hyperglycemia in Compound 48/80 or pilocarpine-treated rats. Hepatology 2: 372-378.
4. 4. J. Zdychova and R. Komers (2005) Emerging role of Akt kinase/protein kinase B signaling in pathophysiology of diabetes and its complications. Physiol Res 54: 1-16.
5. 5. S. Kagawa, Y. Soeda, H. Ishihara, T. Oya, M. Sasahara, S. Yaguchi, R. Oshita, T. Wada, H. Tsuneki and T. Sasaoka (2008) Impact of transgenic overexpression of SH2-containing inositol 5'-phosphatase 2 on glucose metabolism and insulin signaling in mice. Endocrinology 149: 642-650.
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