Up-regulation of Muscle Uncoupling Protein 3 Gene Expression by Calcium Channel Blocker, Benidipine Hydrochloride in Rats

Author:

SAKANE Naoki1,KOTANI Kazuhiko1,HIOKI Chizuko2,YOSHIDA Toshihide2,KAWADA Teruo3

Affiliation:

1. Department of Preventive Medicine, Clinical Research Institute, Center for Endocrine and Metabolic Disease, National Hospital Organization Kyoto Medical Center

2. Department of Endocrinology, Diabetes and Metabolism, Graduate School of Medical Science, Kyoto Prefectural University of Medicine

3. Laboratory of Molecular Function of Food, Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University

Publisher

Japan Endocrine Society

Subject

Endocrinology,Endocrinology, Diabetes and Metabolism

Reference26 articles.

1. 1. Scholz H (1997) Pharmacological aspects of calcium channel blockers. Cardiovasc Drug Ther 10: 869-872.

2. 3. Kitakaze M, Karasawa A, Kobayashi H, Tanaka H, Kuzuya T, Hori M (1999) Benidipine: A new Ca 2+ channel blocker with a cardioprotective effect. Cardiovasc Drug Rev 17: 1-15.

3. 4. Tanaka H, Waki Y, Ito R, Kashitani J, Yamanami S, Saijo T, Ikenaga J, Hara T (1990) Toxicity study of benidipine hydrochloride (1 st report): acute toxicity in mice and rats, subacute and chronic oral toxicity studies of benidipine hydrochloride in rats. Clin Rep 24: 1045-1109. (in Japanese)

4. 5. Tanaka H, Waki Y, Ikenaga T, Kashitani J, Yamanami S, Saijo T, Ikenaga J, Hara T (1990) Toxicity study of benidipine hydrochloride (2 nd report): acute, subacute and chronic oral toxicity studies of benidipine hydrochloride in dogs. Clin Rep 24: 1811-1860. (in Japanese)

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