The association between impaired proinsulin processing and type 2 diabetes mellitus in non-obese Japanese individuals
Author:
Affiliation:
1. Third Department of Internal Medicine, Division of Diabetes, Endocrinology and Metabolism, Kyorin University School of Medicine, Tokyo 181-8611, Japan
2. Division of Clinical Laboratory, Shimada Municipal Hospital, Shizuoka 427-8501, Japan
Publisher
Japan Endocrine Society
Subject
Endocrinology,Endocrinology, Diabetes and Metabolism
Reference41 articles.
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2. 2. Roder ME, Porte D, Jr., Schwartz RS, Kahn SE (1998) Disproportionately elevated proinsulin levels reflect the degree of impaired B cell secretory capacity in patients with noninsulin-dependent diabetes mellitus. J Clin Endocrinol Metab 83: 604-608.
3. 3. Leahy JL, Bonner-Weir S, Weir GC (1992) Beta-cell dysfunction induced by chronic hyperglycemia. Current ideas on mechanism of impaired glucose-induced insulin secretion. Diabetes Care 15: 442-455.
4. 4. Saad MF, Kahn SE, Nelson RG, Pettitt DJ, Knowler WC, et al. (1990) Disproportionately elevated proinsulin in Pima Indians with noninsulin-dependent diabetes mellitus. J Clin Endocrinol Metab 70: 1247-1253.
5. 5. Yoshioka N, Kuzuya T, Matsuda A, Taniguchi M, Iwamoto Y (1988) Serum proinsulin levels at fasting and after oral glucose load in patients with type 2 (non-insulin-dependent) diabetes mellitus. Diabetologia 31: 355-360.
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