A novel mechanism for the inhibition of type 2 iodothyronine deiodinase by tumor necrosis factor α: involvement of proteasomal degradation

Author:

Ogiwara Takayuki1,Araki Osamu1,Morimura Tadashi1,Tsunekawa Katsuhiko1,Mori Masatomo2,Murakami Masami1

Affiliation:

1. Department of Clinical Laboratory Medicine, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan

2. Department of Medicine and Molecular Sciences, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan

Publisher

Japan Endocrine Society

Subject

Endocrinology,Endocrinology, Diabetes and Metabolism

Reference49 articles.

1. 1. Larsen PR (1996) Thyroid hormone transport, cellular uptake, metabolism and molecular action. In DeGroot LJ, Larsen PR and Hennermann G (ed) The thyroid and its disease. Churchill Livingstone, New York: 61-111.

2. 2. Leonard JL, Koehrle J (1996) Intracellular pathways of iodothyronine metabolism. In: LE Braverman & RD Utiger (ed) Werner and Ingbar’s the thyroid: a fundamental and clinical text, edn 7. Lippincott-Raven, Philadelphia: 125-161.

3. 3. Larsen PR (1996) Mammalian type 2 deiodinase sequences: finally, the end of the beginning. J Clin Invest 98: 242-243.

4. 4. Murakami M, Araki O, Hosoi Y, Kamiya Y, Morimura T, Ogiwara T, Mizuma H, Mori M (2001) Expression and regulation of type II iodothyronine deiodinase in human thyroid gland. Endocrinology 142: 2961-2967.

5. 5. Croteau W, Davey JC, Galton VA, St Germain DL (1996) Cloning of the mammalian type II iodothyronine deiodinase: A selenoprotein differentially expressed and regulated in human and rat brain and other tissues. J Clin Invest 98: 405-417.

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