Switching from the tablet to the powder formulation of levothyroxine corrects severe hypothyroidism in a patient with lactose intolerance
Author:
Affiliation:
1. Department of Endocrinology and Metabolism, Dokkyo Medical University, Tochigi 321-0293, Japan
2. Department of Infection Control and Clinical Laboratory Medicine, Dokkyo Medical University, Tochigi 321-0293, Japan
Publisher
Japan Endocrine Society
Subject
Endocrinology,Endocrinology, Diabetes and Metabolism
Link
https://www.jstage.jst.go.jp/article/endocrj/69/8/69_EJ21-0656/_pdf
Reference15 articles.
1. 1 Hays MT (1991) Localization of human thyroxine absorption. Thyroid 1: 241–248.
2. 2 Virili C, Antonelli A, Santaguida MG, Benvenga S, Centanni M (2019) Gastrointestinal malabsorption of thyroxine. Endocr Rev 40: 118–136.
3. 3 de Carvalho GA, Paz-Filho G, Mesa Junior C, Graf H (2018) Management of endocrine disease: pitfalls on the replacement therapy for primary and central hypothyroidism in adults. Eur J Endocrinol 178: R231–R244.
4. 4 Muñoz-Torres M, Varsavsky M, Alonso G (2006) Lactose intolerance revealed by severe resistance to treatment with levothyroxine. Thyroid 16: 1171–1173.
5. 5 Ruchała M, Szczepanek-Parulska E, Zybek A (2012) The influence of lactose intolerance and other gastro-intestinal tract disorders on L-thyroxine absorption. Endokrynol Pol 63: 318–323.
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1. Optimizing Levothyroxine replacement in primary care practice;Hypothyroidism - Causes, Screening and Therapeutic Approaches [Working Title];2024-09-02
2. Lactose intolerance and levothyroxine malabsorption: a review of the literature and report of a series of patients treated with liquid L-T4 without lactose;Frontiers in Endocrinology;2024-04-11
3. Drug forms of levothyroxine. Is there room for innovation in hypothyroidism treatment?;Clinical and experimental thyroidology;2023-07-14
4. Levothyroxine: Conventional and Novel Drug Delivery Formulations;Endocrine Reviews;2022-11-22
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