Administration of Recombinant Human Growth Hormone Normalizes GH-IGF1 Axis and Improves Malnutrition-related Disorders in Patients with Anorexia Nervosa

Author:

HASHIZUME Kiyoshi1,SUZUKI Satoru1,KOMATSU Ai1,HIRAMATSU Kunihide1,MORI Jun-ichiro1,YAMAZAKI Masanori1,TAKEDA Teiji1,KAKIZAWA Tomoko1,MIYAMOTO Takahide1,KOIZUMI Yoichi1,ICHIKAWA Kazuo1

Affiliation:

1. Department of Aging Medicine and Geriatrics, Institute on Aging and Adaptation, Shinshu University Graduate School of Medicine

Publisher

Japan Endocrine Society

Subject

Endocrinology,Endocrinology, Diabetes and Metabolism

Reference29 articles.

1. 1. Rubin RT, Kayre WH (2001) Anorexia nervosa and other eating disorders. In: DeGroot LJ, Jameson JL (eds) Endocrinology, 4th ed. Saunders, Philadelphia, 631-641.

2. 2. Stoving RK, Flyvbjerg A, Frystyk J, Fisker S, Hangaard J, Hansen-Nord M, Hagen C (1999) Low serum levels of free and total insulin-like growth factor I (IGF-I) in patients with anorexia nervosa are not associated with increased IGF-binding protein-3 proteolysis. J Clin Endocrinol Metab 84: 1346-1350.

3. A review of endocrine changes in anorexia nervosa

4. 4. Portes ES, Oliveira JH, MacCagnan P, Abucham J (2000) Changes in serum thyroid hormones levels and their mechanisms during long-term growth hormone (GH) replacement therapy in GH deficient children. Clin Endocrinol (Oxf) 53: 183-189.

5. 5. Wolthers T, Lemming L, Grofte T (1996) Effects of growth hormone on serum lipids and lipoproteins: possible significance of increased peripheral conversion of thyroxine to triiodothyronine. Metabolism 45: 1016-1020.

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