Spatially Modulated Proton Minibeams Results in the Same Increase of Lifespan as a Uniform Target Dose Coverage in F98-Glioma-Bearing Rats

Author:

Lamirault Charlotte1,Brisebard Elise2,Patriarca Annalisa3,Juchaux Marjorie1,Crepin Delphine1,Labiod Dalila4,Pouzoulet Frederic4,Sebrie Catherine5,Jourdain Laurene5,Le Dudal Marine2,Hardy David2,De Marzi Ludovic3,Dendale Remi3,Jouvion Gregory2,Prezado Yolanda6

Affiliation:

1. Laboratoire Imagerie et Modelisation pour la Neurobiologie et la Cancerologie, CNRS-Paris 7-Paris 11, Campus d'Orsay, France

2. Department of Global Health, Experimental Neuropathology Unit, Institut Pasteur, 75015 Paris, France

3. Radiation Oncology Department, Centre de Protonthérapie d'Orsay

4. Radiation Oncology Department, Experimental Radiotherapy Platform Institut Curie, University Paris Saclay, Orsay, France

5. BioMaps, Université Paris-Saclay, CEA, CNRS, Inserm,Service Hospitalier Frédéric Joliot, 91401 Orsay, France

6. Institut Curie, University Paris Saclay, PSL Research University, Inserm U 1021-CNRS UMR 3347, Orsay, France

Publisher

Radiation Research Society

Subject

Radiology Nuclear Medicine and imaging,Radiation,Biophysics

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