Tumour targeting: biological factors and formulation advances in injectable lipid nanoparticles-Reference-Cited by-同舟云学术

Tumour targeting: biological factors and formulation advances in injectable lipid nanoparticles

Published:2005-04 Issue:4 Volume:57 Page:411-421
ISSN:0022-3573
Container-title:Journal of Pharmacy and Pharmacology
language:en
Short-container-title:

Author:

Shenoy V S¹,Vijay I K¹,Murthy R S R¹

Affiliation:

1. New Drug Delivery Systems Laboratory, Pharmacy Department, Donors Plaza, Opp. University Main Office, M S University of Baroda, Fatehgunj, Vadodara-390 002, India

Abstract

Abstract Cancer chemotherapeutic agents are often administered systemically. Following systemic administration, numerous biological factors associated with the tumours influence the delivery of the drugs to the tumours. These factors have been extensively studied for the last 2 decades. The influence of these biological factors has brought about a drastic change in the design of drug delivery systems to solid tumours. This review discusses the various biological factors influencing drug delivery to tumours and the subsequent development of injectable delivery systems (i.e., lipid-based nanoparticles (SLNs)) for adequate delivery of drug to solid tumours.

Publisher

Oxford University Press (OUP)

Subject

Pharmaceutical Science,Pharmacology

Link

http://academic.oup.com/jpp/article-pdf/57/4/411/36735599/0022357055894.pdf

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