Abstract
Evaluating the efficacy of the treatment regimens used during the year, the benefits of using magnesium and potassium gluconic acid, eplerenone or rivaroxabane with basic therapy (BT) have been proven. In all of the groups under study, there was a positive trend in the treatment process in terms of reducing the number of heart rhythm disturbances. However, a probable decrease in the number of supraventricular and ventricular extrasystoles was noted in groups of patients with the use of salts of magnesium and potassium gluconic acid or rivaroxabane against the background of BT. The results of Holter monitoring of the electrocardiogram showed that the treatment regimens studied were effective in reducing the rate of myocardial ischemia. The treatment of patients with rivaroxiban resulted in a decrease in the total duration of myocardial ischemia per day by 51.93 %. Consequently, an intensive reduction of manifestations of myocardial ischemia and cardiac rhythm disturbance with the use of rivaroxaban on the background of BT in patients with chronic heart failure after myocardial infarction has been established.
Publisher
LLC Information and Research Center Likarska Sprava
Reference8 articles.
1. Voronkov L. G. Supportive diuretic therapy in patients with CHF: questions and answers // Heart failure. – 2016. – № 2. – P. 44–51.
2. Radionova Yu. V. Effects of complex treatment of chronic heart failure of ischemic origin associated with diabetes mellitus // Klin. pharmacy. – 2013. – № 2. – P. 30–33.
3. Anand S., Yusuf S. Oral anticoagulant therapy in patients with coronary artery disease: a meta-analysis // JAMA. – 1999. – Vol. 282. – P. 2058–2067.
4. ACCF/AHA Guideline for the Management of ST-Elevation Myocardial Infarction // JACC. – 2013. – Vol. 61, N 4. – P. 78–140.
5. Fuster V., Badimon J. J., Chesebro J. H. et al. Atherothrombosis: mechanisms and clinical therapeutic approaches // Vascular Med. – 1998. – N 3. – P. 231–239.