Factor VIIa/factor X製剤と高用量recombinant factor VIIa製剤の併用療法を施行した血友病Bインヒビター1症例の凝固能評価
Author:
Affiliation:
1. Department of Pediatrics, Mutsu General Hospital
2. Medical Affairs Section, R&D Coordination & Administration Department, KM Biologics Co., Ltd.
3. Section 2, Research Department, KM Biologics Co., Ltd.
Publisher
Japanese Society on Thrombosis and Hemostasis
Subject
General Medicine
Link
https://www.jstage.jst.go.jp/article/jjsth/34/3/34_2023_JJTH_34_3_374-380/_pdf
Reference23 articles.
1. 1) Hay CRM, Brown S, Collins PW, et al.: The diagnosis and management of factor VIII and IX inhibitors: A guideline from the United Kingdom Haemophilia Centre Doctors Organization. Br J Haematol 133: 591–605, 2006.
2. 2) Hayashi T, Tanaka I, Shima M, et al.: Unresponsiveness to factor VIII inhibitor bypassing agents during hemostatic treatment for life-threatening massive bleeding in a patient with hemophilia A and a high responding inhibitor. Haemophilia 10: 397–400, 2004.
3. 3) インヒビター保有先天性血友病患者に対する止血治療ガイドライン作成委員会:インヒビター保有先天性血友病患者に対する止血治療ガイドライン2013年改訂版.血栓止血誌 24: 640–658, 2013.
4. 4) Schneiderman J, Nugent DJ, Young G: Sequential therapy with activated prothrombin complex concentrate and recombinant factor VIIa in patients with severe haemophilia and inhibitors. Haemophilia 10: 347–351, 2004.
5. 5) Schneiderman J, Rubin E, Nugent DJ, et al.: Sequential therapy with activated prothrombin complex concentrates and recombinant FVIIa in patients with severe haemophilia and inhibitors: Update of our previous experience. Haemophilia 13: 244–248, 2007.
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