PARAMETERS ASSOCIATED WITH ACUTE APPENDICITIS IN PREGNANCY

Abstract

Objective Acute appendicitis is the most common cause of nonobstetric acute abdomen in pregnant women. The fact that sympathomatology brings to mind primarily obstetric causes in pregnant patients, physiological leukocytosis is observed throughout pregnancy, and limitations in imaging methods cause confusion in the diagnosis. This makes the need for detailed evaluation in laboratory parameters inevitable. The aim of the study is to reveal the relationship of laboratory parameters such as neutrophil lymphocyte ratio (NLR), platelet lymphocyte ratio (PLR), lymphopenia with the diagnosis of appendicitis and its diagnostic power. Material and Method In the evaluation of 31 patients who were operated on with the diagnosis of acute appendicitis during pregnancy between January 2017 and February 2021 were evaluated. Correlation and roc analysis were performed by evaluating patients' demographic data, laboratory results, ultrasonography or magnetic resonance imaging reports and intraoperative findings. Results A significant correlation was found between detection of appendicitis in exploration and increased neutrophils, leukocytosis, and NLR (p: 0.014, p: 0.015, p: 0.020, respectively). Again, the presence of lymphopenia, high NLR and increased palletelet / lymphocyte ratio (PLR) were found to be associated with prolonged hospitalization (p:0.037, p:0.008, and p:0.024, respectively). Roc analysis also showed that leukocytosis [AUC: 0.938 (95%CI: 0-1.00, p:0.019)], neutrophil elevation [AUC: 0.938 (95%CI: 0-1.00, p:0.019)] and NLR [AUC: 0.917 (0-1.00 p: 0.025)] was found to have the power to reveal the presence of significant acute appendicitis. Conclusion It is recommended to use hemogram parameters and imaging methods effectively in the diagnosis of acute appendicitis in pregnants.