A Study on the Phenolic Acid Compositions, Antioxidant Activities and Cell Cytotoxicity of Red Cabbage Leaf Extract as Functional Cosmetic Raw Materials

Abstract

The total polyphenol and flavonoid content, phenolic acid composition and contents, some antioxidant activity effects, and cytotoxicity against HaCaT cell line of red cabbage leaf hot water extract were investigated as follows. As a result of measuring the total polyphenol and flavonoid content, the total flavonoid content was slightly higher than the total polypheol content. As a result of analyzing the composition and contents of phenolic acid and flavonoid, two types of phenolic acid were identified, but flavonoid was not identified. DPPH and ABTS radical scavenging activity, and FRAP tended to increase as the treatment concentration increased, and this tendency was found to have statistical significance (p<.001). The degree of cytotoxicity to the HaCaT cell line was found to increase with increasing treatment concentration, and at a treatment concentration of 100 μg/ml, cell growth was reduced by about 22% compared to the control. Therefore, the hot-water extract of red cabbage leaves has significant antioxidant activity, and it is considered that it may be used as a natural antioxidant for functional cosmetic raw materials. However, it is considered that there is a need for more continuous research on the degree of cytotoxicity according to the cell line.