Study on the polymorphism of fibroblast growth facorreceptor (FGFR1) in sheep

Abstract

The polymorphisms of fibroblast growth factor receptor (FGFR1) were detected in large-tailed Han sheep, small-tailed Han sheep, Yuxi fat-tailed sheep and Lanzhou large-tailed sheep by PCR product sequencing technology. The results showed that FGFR1 gene had 4 mutation sites in large-tailed Han sheep, small-tailed Han sheep, Yuxi fat-tailed sheep and Lanzhou large-tailed sheep, including T558C, G342A, G417A and G420A. FGFR1 gene sequences of different species clustering showed that sheep, buffalo and Tibetan antelope clustered together firstly, suggesting that the three phylogenetic species had a close relationship.