Mesenchymal Stem Cell Therapy in a Case of Bilateral Chronic Osteoarthritis Occurring in Articulatio Genu in a Dog of Cane Corso Breed

Abstract

Background: In this study, mesenchymal stem cell therapy and the findings were discussed in a bilateral chronic osteoarthritis case in a Cane Corso breed dog. Methods: A patient was brpought to the clinic with the complaint of lameness, malaise, fear, anxiety and reluctance in running, stair climbing and descending movements. In the orthopedic examination, Art. Genu was found to have pain in flexion and extension movements and on radiological examination, joint space was reduced and bilateral chronic osteoarthritis was found. The patient was sedated and mesenchymal stem cells were injected into both knee joints. These procedures were repeated twice with an interval of three weeks. Result: The joint space of both knees widened and the joint fluid increased after the treatment. In addition, there was a relief in flexion and extension movements on the both knees. The patient’s lameness decreased and he did not experience uneasiness when going up and down the stairs and there was a significant improvement. It was determined that mesenchymal stem cell therapy gave a positive response in the current osteoarthritis case. It has been concluded that this method can be applied as an alternative to steroids, NSAID (Nonsteroid anti-inflammatory drugs) and GAG (Glycosaminoglycan) applications in similar cases.