Evaluation of autologous and homologous platelet rich plasma as a surgical wound healing promoter in rabbits
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Published:2018-06-11
Issue:00
Volume:
Page:
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ISSN:0976-0555
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Container-title:Indian Journal of Animal Research
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language:
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Short-container-title:IJAR
Author:
Tahir Muhammad Shahid,Durrani Uzma Farid,Mahmood Asim Khalid,Akhtar Raheela,Hussain Rashid,Hussain Abid,Matloob Khizar,Zahid Beenish
Abstract
The present study compared the efficacy of autologous and homologous platelet rich plasma (PRP) as a surgical wound healing promoter in rabbits. Sixteen adult healthy rabbits were divided into two groups i.e. A and B. Group A was treated with autologous platelet rich plasma (APRP) and group B was treated with homologous platelet rich plasma (HPRP). Both groups were operated for skin grafting (auto grafting) at two (PRP treated experimental and control) sites. Clinical evaluation of PRP was performed by using macroscopic (edema, exudation, coloration, temperature, cosmetic appearance and healing status) and microscopic (acute inflammation, fibroblast proliferation and granulation tissue proliferation) parameters. The healing status, coloration and cosmetic appearance of APRP treated group were more satisfactory than HPRP treated group. APRP group also showed less inflammation, edema and more granular tissue proliferation as compare to HPRP group. It was concluded that autologous PRP is an efficient surgical wound healing promoter in rabbits.
Publisher
Agricultural Research Communication Center
Subject
General Veterinary,Animal Science and Zoology
Cited by
1 articles.
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