Potent neutralization by monoclonal human IgM against SARS‐CoV‐2 is impaired by class switch

Author:

Callegari Ilaria12ORCID,Schneider Mika1,Berloffa Giuliano1ORCID,Mühlethaler Tobias3,Holdermann Sebastian12ORCID,Galli Edoardo12ORCID,Roloff Tim45,Boss Renate6,Infanti Laura7,Khanna Nina8,Egli Adrian45ORCID,Buser Andreas7ORCID,Zimmer Gert910ORCID,Derfuss Tobias12,Sanderson Nicholas S R12ORCID

Affiliation:

1. Department of Biomedicine University of Basel and University Hospital Basel Basel Switzerland

2. MS Center, Neurologic Clinic and Policlinic, Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB) University Hospital Basel University of Basel Basel Switzerland

3. Biophysics Facility Biozentrum University of Basel Basel Switzerland

4. Applied Microbiology Research Department of Biomedicine University of Basel Basel Switzerland

5. Clinical Bacteriology and Mycology University Hospital Basel Basel Switzerland

6. Federal Food Safety and Veterinary Office Bern Switzerland

7. Regional Blood Transfusion Service, Swiss Red Cross Basel Switzerland

8. Infectious Diseases and Hospital Epidemiology University Hospital Basel Basel Switzerland

9. Institute of Virology and Immunology Bern & Mittelhäusern Switzerland

10. Department of Infectious Diseases and Pathobiology Vetsuisse Faculty University of Bern Bern Switzerland

Funder

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung

Publisher

EMBO

Subject

Genetics,Molecular Biology,Biochemistry

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