The Hippo/ YAP pathway interacts with EGFR signaling and HPV oncoproteins to regulate cervical cancer progression

Author:

He Chunbo12,Mao Dagan13,Hua Guohua12,Lv Xiangmin1,Chen Xingcheng4,Angeletti Peter C5,Dong Jixin4,Remmenga Steven W14,Rodabaugh Kerry J1,Zhou Jin16,Lambert Paul F7,Yang Peixin8,Davis John S149,Wang Cheng14

Affiliation:

1. Olson Center for Women's Health Department of Obstetrics & Gynecology University of Nebraska Medical Center Omaha NE USA

2. College of Animal Science and Technology Huazhong Agricultural University Wuhan China

3. College of Animal Science and Technology Nanjing Agricultural University Nanjing China

4. Fred & Pamela Buffett Cancer Center University of Nebraska Medical Center Omaha NE USA

5. Nebraska Center for Virology School of Biological Sciences University of Nebraska‐Lincoln Lincoln NE USA

6. Department of Obstetrics and Gynecology Urumqi General Hospital of Lanzhou Military Region Urumqi China

7. Department of Oncology McArdle Laboratory for Cancer Research University of Wisconsin School of Medicine and Public Health Madison WI USA

8. Department of Obstetrics, Gynecology & Reproductive Sciences University of Maryland School of Medicine Baltimore MD USA

9. Omaha Veterans Affairs Medical Center Omaha NE USA

Funder

Eunice Kennedy Shriver National Institute of Child Health and Human Development

The Olson Center for Women's Health

The Fred & Pamela Buffett Cancer Center

The National Institute of Food and Agriculture

Publisher

EMBO

Subject

Molecular Medicine

Reference77 articles.

1. Human papillomavirus type 16 E6 and E7 cooperate to increase epidermal growth factor receptor (EGFR) mRNA levels, overcoming mechanisms by which excessive EGFR signaling shortens the life span of normal human keratinocytes;Akerman GS;Cancer Res,2001

2. YAP oncogene overexpression supercharges colon cancer proliferation

3. E7 protein of human papilloma virus‐16 induces degradation of retinoblastoma protein through the ubiquitin‐proteasome pathway;Boyer SN;Cancer Res,1996

4. Estrogen contributes to the onset, persistence, and malignant progression of cervical cancer in a human papillomavirus-transgenic mouse model

5. Worldwide Human Papillomavirus Etiology of Cervical Adenocarcinoma and Its Cofactors: Implications for Screening and Prevention

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