Therapeutic inhibition of TRF 1 impairs the growth of p53 ‐deficient K‐Ras G12V ‐ induced lung cancer by induction of telomeric DNA damage-Reference-Cited by-同舟云学术

Therapeutic inhibition of TRF 1 impairs the growth of p53 ‐deficient K‐Ras G12V ‐ induced lung cancer by induction of telomeric DNA damage

Published:2015-05-13 Issue:7 Volume:7 Page:930-949
ISSN:1757-4676
Container-title:EMBO Molecular Medicine
language:en
Short-container-title:EMBO Mol Med

Author:

García‐Beccaria María¹,Martínez Paula¹,Méndez‐Pertuz Marinela¹,Martínez Sonia²,Blanco‐Aparicio Carmen²,Cañamero Marta³,Mulero Francisca⁴,Ambrogio Chiara⁵,Flores Juana M⁶,Megias Diego⁷,Barbacid Mariano⁴,Pastor Joaquín²,Blasco Maria A¹

Affiliation:

1. Telomeres and Telomerase Group Molecular Oncology Program Spanish National Cancer Research Centre (CNIO) Madrid Spain

2. Experimental Therapeutics Program Spanish National Cancer Research Centre (CNIO) Madrid Spain

3. Histopathology Unit Biotechnology Program Spanish National Cancer Research Centre (CNIO) Madrid Spain

4. Molecular Imaging Unit Biotechnology Program Spanish National Cancer Research Centre (CNIO) Madrid Spain

5. Experimental Oncology Molecular Oncology Program Spanish National Cancer Research Centre (CNIO) Madrid Spain

6. Animal Surgery and Medicine Department Faculty of Veterinary Science Complutense University of Madrid Madrid Spain

7. Microscopy Unit Biotechnology Program Spanish National Cancer Research Centre (CNIO) Madrid Spain

Publisher

EMBO

Subject

Molecular Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.15252/emmm.201404497

Reference80 articles.

1. Modeling Lung Cancer Evolution and Preclinical Response by Orthotopic Mouse Allografts

2. Germline Mutations in Shelterin Complex Genes Are Associated With Familial Glioma

3. Conditional TRF1 knockout in the hematopoietic compartment leads to bone marrow failure and recapitulates clinical features of dyskeratosis congenita

4. Increased expression of telomere length regulating factors TRF1, TRF2 and TIN2 in patients with adult T-cell leukemia

5. Telomere length, stem cells and aging

Cited by 47 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Targeting shelterin proteins for cancer therapy;Drug Discovery Today;2024-08

2. Telomere-related DNA damage response pathways in cancer therapy: prospective targets;Frontiers in Pharmacology;2024-06-07

3. Shaping DNA damage responses: Therapeutic potential of targeting telomeric proteins and DNA repair factors in cancer;Current Opinion in Pharmacology;2024-06

5. Deubiquitinases in cancer;Nature Reviews Cancer;2023-11-07