Hepatic PPARα function and lipid metabolic pathways are dysregulated in polymicrobial sepsis

Author:

Van Wyngene Lise12ORCID,Vanderhaeghen Tineke12,Timmermans Steven12,Vandewalle Jolien12ORCID,Van Looveren Kelly12,Souffriau Jolien12,Wallaeys Charlotte12,Eggermont Melanie12,Ernst Sam12,Van Hamme Evelien3,Gonçalves Amanda3,Eelen Guy45ORCID,Remmerie Anneleen12,Scott Charlotte L12,Rombouts Caroline6,Vanhaecke Lynn6,De Bus Liesbet7,Decruyenaere Johan7ORCID,Carmeliet Peter45ORCID,Libert Claude12ORCID

Affiliation:

1. Center for Inflammation Research VIB Ghent Belgium

2. Department of Biomedical Molecular Biology Ghent University Ghent Belgium

3. Bio Imaging Core VIB Center for Inflammation Research Ghent Belgium

4. Laboratory of Angiogenesis and Vascular Biology VIB Center for Cancer Biology VIB Leuven Belgium

5. Laboratory of Angiogenesis and Vascular Metabolism Department of Oncology and Leuven Cancer Institute (LKI) KU Leuven Leuven Belgium

6. Faculty of Veterinary Medicine Department of Veterinary Public Health and Food Safety Laboratory of Chemical Analysis Ghent University Ghent Belgium

7. Department of Critical Care Medicine Ghent University Hospital Ghent Belgium

Funder

Fonds Wetenschappelijk Onderzoek

Publisher

EMBO

Subject

Molecular Medicine

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