Anti‐tumor effects of PIM / PI 3K/ mTOR triple kinase inhibitor IBL ‐302 in neuroblastoma-Reference-Cited by-同舟云学术

Anti‐tumor effects of PIM / PI 3K/ mTOR triple kinase inhibitor IBL ‐302 in neuroblastoma

Published:2019-07-16 Issue:8 Volume:11 Page:
ISSN:1757-4676
Container-title:EMBO Molecular Medicine
language:en
Short-container-title:EMBO Mol Med

Author:

Mohlin Sofie¹^ORCID,Hansson Karin²,Radke Katarzyna²,Martinez Sonia³^ORCID,Blanco‐Apiricio Carmen³,Garcia‐Ruiz Cristian²^ORCID,Welinder Charlotte⁴,Esfandyari Javanshir²,O'Neill Michael⁵,Pastor Joaquin³,Stedingk Kristoffer¹⁶,Bexell Daniel²^ORCID

Affiliation:

1. Division of Pediatrics Department of Clinical Sciences Lund University Lund Sweden

2. Department of Laboratory Medicine Translational Cancer Research Lund University Cancer Center Lund University Lund Sweden

3. Experimental Therapeutics Programme Spanish National Cancer Research Centre (CNIO) Madrid Spain

4. Division of Oncology and Pathology Department of Clinical Sciences Lund Lund University Lund Sweden

5. Inflection Biosciences Ltd Blackrock Ireland

6. Department of Oncogenomics University Medical Center University of Amsterdam Amsterdam The Netherlands

Funder

Vetenskapsrådet

Cancerfonden

Barncancerfonden

Region Skåne

Magnus Bergvalls Stiftelse

Crafoordska Stiftelsen

Jeanssons Stiftelser

Berth von Kantzows Stiftelse

Ministerio de Ciencia e Innovación

Publisher

EMBO

Subject

Molecular Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.15252/emmm.201810058

Reference41 articles.

1. Heterogeneity of neuroblastoma cell identity defined by transcriptional circuitries

2. Neuroblastoma patient‐derived orthotopic xenografts retain metastatic patterns and geno‐ and phenotypes of patient tumours

3. Patient‐derived xenograft models reveal intratumor heterogeneity and temporal stability in neuroblastoma;Braekeveldt N;Cancer Res,2018

4. PIM Kinases Are a Potential Prognostic Biomarker and Therapeutic Target in Neuroblastoma

5. Downregulation of MYCN through PI3K Inhibition in Mouse Models of Pediatric Neural Cancer

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