Mitochondrial HSF1 triggers mitochondrial dysfunction and neurodegeneration in Huntington's disease

Author:

Liu Chunyue12,Fu Zixing1,Wu Shanshan2,Wang Xiaosong1,Zhang Shengrong1,Chu Chu2,Hong Yuan2,Wu Wenbo1,Chen Shengqi1,Jiang Yueqing1,Wu Yang3ORCID,Song Yongbo4,Liu Yan2ORCID,Guo Xing15ORCID

Affiliation:

1. State Key Laboratory of Reproductive Medicine Key Laboratory of Human Functional Genomics of Jiangsu Province Department of Neurobiology Interdisciplinary InnoCenter for Organoids School of Basic Medical Sciences Nanjing Medical University Nanjing China

2. State Key Laboratory of Reproductive Medicine Interdisciplinary InnoCenter for Organoids Institute for Stem Cell and Neural Regeneration School of Pharmacy Nanjing Medical University Nanjing China

3. State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics Key Laboratory of Magnetic Resonance in Biological Systems Wuhan Center for Magnetic Resonance, Innovation Academy for Precision Measurement Science and Technology Chinese Academy of Sciences Wuhan China

4. Department of Pharmacology Shenyang Pharmaceutical University Shenyang China

5. Department of Endocrinology Sir Run Run Hospital Nanjing Medical University Nanjing Jiangsu China

Funder

National Key Research and Development Program of China

National Natural Science Foundation of China

Innovative Team of Jiangsu Province

Publisher

EMBO

Subject

Molecular Medicine

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